The root is used as medicine. or Healthy Lifestyle Brands. 6 Ways To Fix That, ASAP. Common Names: Bushy Knotweed, Japanese Bushy Knotweed, Tiger Cane, Giant Knotweed, Some people may refer to this herb as Japanese Bushy Knotweed Root and Rhizome Botanical Name: Polygonum cuspidatum; Rhizome Pin Yin Name: Hu Zhang Each member of our research team is required to have no conflicts of interest, including with supplement Knotweed rhizomes and young sprouts are used in a traditional Asian medicine as laxatives, and occasionally as foods. We have a strict editorial process. An employee wears a protective face mask at a traditional Chinese medicine store in Beijing on Saturday. All factual claims are followed by specifically-applicable references. https://examine.com/supplements/japanese-knotweed/, © 2011-2020 Examine.com Inc | Privacy | Terms of Service | Disclaimer | About Us | Contact Examine.com. Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy. What makes this herb favorable is that while it is quite effective at activation circulation, it is also very cooling in nature, making it useful in cases of excess heat. Therapeutic Uses, Benefits and Claims of Chinese Knotweed (Fo-Ti) Chinese Knotweed (Polygonum multiflorum) – ©The Herbal Resource Fo-ti is one of principal ingredients of the “Shou Wu Chih,” which is one of the Chinese patent medicines. Even though it has been used for centuries in traditional Chinese medicine, further research is needed to better assess safety, effectiveness, and appropriate dosing. Information tailored to you, updated every month. Japanese knotweed is quickly becoming the preferred source of resveratrol. HighBeam Research. Hu zhang is the Chinese name given to a plant with the scientific name of Polygonum cuspidatum. Because Hu Zhang contains resveratrol, a compound that may possess growth factor-inhibiting actions, this agent should not be given to children. The safety of Hu Zhang during pregnancy, breastfeeding, and childhood has not been established. ... are also studying the potential use of a plant commonly known as Japanese knotweed … Bonus: unlock the supplement Human Effect Matrix and all health topics on Examine.com. The study in question measured nF-kB activity and noted a 25% decrease, which is somewhat novel (not a common measurement) and to quite a large degree; may be related to the, Appears to reduce oxidative biomarkers, requires more evidence to gauge potency and reliability thereof, A decrease in TNF-a has been noted following oral consumption of japanese knotweed, Blood glucose appears to be unaffected following ingestion of Japanese knotweed in otherwise healthy lean persons, No significant influence on HDL-C in otherwise healthy lean persons, No significant alterations in fasting insulin levels seen with treatment, Insulin sensitivity is unaffected in otherwise healthy lean persons given this supplement, LDL-C appears to be unaffected, but testing has not been conducted in metabolically unwell persons, No significant influence on leptin in otherwise healthy and lean individuals, No significant alterations in cholesterol seen with Japanese Knotweed ingestion, No significant influence of Japanese Knotweed on triglycerides. Huzhang (Japanese Knotweed) has been used in traditional Chinese medicine as well as in Japan and Korea for many years. We are 100% backed by science. Examine.com does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. During the 1800s, Polygonum cuspidatum was introduced to Europe and America as an ornamental plant. ©Copyright 2020 Healthy Lifestyle Brands, LLC. Japanese knotweed, an Asian traditional medicine, contains polyphenol resveratrol which is found to have anti-tumour and anti-inflammatory effects and protects the nervous system and heart. That's why we don’t sell any advertising or supplements. Japanese knotweed (Polygonum cuspidatum) is, herbaceous perennial plant, native to eastern Asia in Japan, Korea and China.In traditional Chinese medicine (TCM), the plant is known as huzhang. Examine.com and its Editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from supplements or practices hosted under the domain of Examine.com. VERY HIGH means that most of the scientific research agrees. www.drweil.com, Feeling Stressed Out? Polygonum Cuspidatum var. Taking it when you are on estrogen replacement therapy or birth control pills might impact the effects of these drugs. Examine.com and its Editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under Examine.com. Arm yourself with the knowledge you need to make the right decisions about your health. Mat Day at Environet took a much more flexible approach and treated me like an individual customer. Japanese Knotweed (Polygonum cuspidatum) Japanese knotweed has been in the armament of Chinese and Japanese herbal traditions for thousands of years. for this page. Japanese knotweed shoots are rich in vitamin A, resveratrol, zinc, manganese, potassium, and vitamin C. Most supplements called ‘resveratrol’ (a powerful antioxidant) are now made with Japanese knotweed. The team includes nutrition researchers, registered Composition analysis of Japanese Knotweed reveals it to be a vessel for Resveratrol (as well as a few other compounds structurally similar to resveratrol and may act in the same way) and anthraquinone compounds that possess slight laxative effects; like Senna root but less potent. 14 June 2018, Make informed decisions about your health, https://examine.com/supplements/japanese-knotweed/, Robust research conducted with repeated double-blind clinical trials, Multiple studies where at least two are double-blind and placebo controlled, Single double-blind study or multiple cohort studies, Uncontrolled or observational studies only. Our independent, unbiased approach reveals what works (and what's a waste of time and money). Traditional Chinese Medicine has used it as a blood­moving herb, to resolve inflammation, stagnation, and poor circulation and also as a supportive herb to counter debility and immune fatigue. Most research on Japanese Knotweed has been pertaining to either suppressing its invasive tendencies, or controlling it to become a large scale producer of Resveratrol for medical or supplemental usage. Cryptolepis sanguinolenta 2. The only current human study used Japanese Knotweed at 200mg daily and standardized to 40mg Resveratrol which was effective. Japanese knotweed also contains vitamins and minerals and has been used in traditional medicine for centuries. Becoming a member also unlocks our study database of 400+ supplements and their effects on 600+ health outcomes. Any third party offering or advertising on this website does not constitute an endorsement by Andrew Weil, M.D. Most of the effects of Japanese Knotweed can be traced back to either the stilbenes (resveratrol) or the anthraquinones (emodin) for the circulatory and gastrointestinal help, respectively. According to a review published in September 2013 in the journal Evidence Based Complementary and Alternative Medicine, pharmacological and clinical studies suggest that Hu Zhang has antiviral, antimicrobial, anti-inflammatory, neuroprotective, and cardio-protective functions. Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more. It is also well known as an herbal support for … Japanese Knotweed Chinese medicine is also a very effective pain reliever, and clears dampness and heat. It also appears to have neuroprotective and antimicrobial activity. Japanese knotweed has been used in Chinese medicine due to its therapeutic properties. Yes! On Sunday the Philippines reported the first death outside of China. 150+ studies summarized across 25 different categories every month. "Japanese Knotweed," Examine.com, published on 30 September 2013, last updated on Polygonum c… You must be logged before you can follow this page. Japanese knotweed is a member of the buckwheat family. You should not use the information on this website for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. Its scientific names include Fallopia japonica and Polygonum cuspidatum. You will be notified when any significant update is made. A broadly systemic plant, Japanese Knotweed Root modulates and enhances immune function, is anti-inflammatory for both arthritic and bacterial inflammations, protects the body against endotoxin damage, and is a potently strong angiogenesis modulator, highly protective of the endothelia of the body. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified Health Care Professional prior to using any nutritional supplementation. Stay Connected With Dr. Weil - Get Free Newsletters Right In Your Inbox, Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. HIGH or The dried root is used medicinally and is listed in the Pharmacopoeia of the People’s Republic of China. dietitians, physicians, and pharmacists. Click here to see the full set of references In a study published in the journal BMC Complementary and Alternative Medicine , researchers from Guangzhou University of Chinese Medicine in China investigated the bioactivity of Japanese knotweed against hepatocellular carcinoma (HCC). According to the Natural Medicines Comprehensive Database there isn’t enough known about Hu Zhang to determine its effectiveness as a treatment for these disorders. Overview Information Knotweed is an herb. Limited trials have been conducted in humans, but it appears to have similar effects to resveratrol due to the resveratrol content. Leonurus japonicusHoutt. Cinnamomum, i.e. Become an Examine.com member to get access to the latest research. This plant is an invasive species yet has been used traditionally in Chinese and Japanese medicine for its benefits on gastrointestinal health and circulatory health (among some other claims such as cancer prevention). This page features 55 references. followed by specifically-applicable references. Japanese Knotweed, or Polygonum Cuspidatum, is a Traditional Chinese Medicine used for circulation and heart health. Hu Zhang is also used as folk medicine in Japan and Korea. In traditional Chinese medicine, Japanese Knotweed is described as bitter and slightly cold, and its uses include supporting the body’s natural detoxification pathways, increasing blood circulation, clearing heat, for various skin concerns, menstruation support, improving liver and cardiovascular health, and as a … Hu Zhang (Polygonum cuspidatum) is the Chinese name for a plant also known as Japanese knotweed and Mexican bamboo. which have been used safely for thousands of years. Reproduction in whole or in part without permission is prohibited. Japanese Knotweed Supreme contains trans-resveratrol, the form best absorbed by the body. Some studies have suggested that resveratrol may have anticancer properties, and may protect heart and brain health. Natural Medicines Comprehensive Database, http://naturaldatabaseconsumer.therapeuticresearch.com/nd/Search.aspx?rn=3&cs=NONMP&s=NDC&pt=100&id=1111&fs=NDC&searchid=45838311, accessed march 30. In China, it is believed that the medication prepared from this plant rejuvenate the body. there is, and how strong these effects are. It is a very good source of resveratrol, and most benefits of Japanese Knotweed may actually just be benefits of Resveratrol. Reviewed by Russell Greenfield, M.D., August, 2016. We have a strict editorial process. Polygonum cuspidatum contains a compound known as polydatin, or piceid. All factual claims are Huan Zhang et al, “A Review of the Pharmocological Effects of the dried root of Polygonum cuspidatum (Hu Zhang) and its Constituents”, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806114/, accessed March 30, 2014A Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents, A Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents, Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents. To use Japanese Knotweed Root tincture for cancer treatment, you will need to work with a healthcare professional to determine a dosage relevant to your treatment plan. All rights reserved. Japanese Knotweed has on your body, how much evidence The dried root is used medicinally and is listed in the Pharmacopoeia of the People’s Republic of China. Become an Examine Personalized member to access the latest nutrition research on over 400 supplements across more than 600 different health goals, outcomes, conditions, and more. Resveratrol in Japanese Knotweed inhibits cancer cells without harming the liver. each outcome. Get our free 5-day course on the essentials of supplementation. Japanese knotweed belongs to the Fallopia genus and Polygonaceae family. Hu Zhang ( Polygonum cuspidatum) is the Chinese name for a plant also known as Japanese knotweed and Mexican bamboo. Hu Zhang may have estrogenic effects. Japonicus is the species of plant most commonly referred to as Japanese Knotweed. ANTI-INFLAMMATORY - Resveratrol is a known anti-inflammatory and antioxidant. Examine.com is intended to be used for educational and information purposes only. For information specific to the activity of resveratrol, see … Studies indicate the most beneficial use to be in pancreatic, breast, and ovarian cancers. In traditional Chinese medicine, BioPure Japanese Knotweed is described as bitter and slightly cold, and its uses include supporting the body’s natural detoxification pathways, increasing blood circulation, clearing heat, for various skin concerns, menstruation support, improving liver and cardiovascular health, and as a diuretic. Traditional Chinese medicine, herbs from the rain forest, South American herbs, Traditional Native American herbs, etc. Hu Zhang is used medicinally to treat atherosclerosis (hardening of the arteries), heart disease, and high cholesterol, as well as constipation, hepatitis, and gallstones. Some studies have used extracts standardized to 20% trans-resveratrol. In traditional Chinese medicine, it is essential in the treatment of menstrual and delivery disorders caused by blood stasis, such as dysmenorrhea, amenorrhea, and postpartum hemorrhage. Scientific research does not always agree. Click here Although there are other bioactives in Japanese Knotweed, it may be prudent to dose it in accordance to the dosing guidelines on the resveratrol page. Kim JY, Gum SN, Paik JK, Lim HH, Kim KC, Ogasawara K, Inoue K, Park S, Jang Y, Lee JH. “Because patients are currently turning to herbal remedies to fill the treatment gaps left by antibiotics, this research is a critical step in helping clinicians, as well as patients, understand which ones may offer the most potential benefit.” According to this study, carried out by Prof. Ying Zhang’s group at the Johns Hopkins Bloomberg School of Public Health, the seven herbal medicines that have the ability to kill B. burgdorferiin test tubes are: 1. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. Our evidence-based analysis on japanese knotweed features In traditional Chinese medicine formulations containing Hu Zhang are prescribed for treating cough, hepatitis, jaundice, amenorrhea, vaginal discharge, joint pain, burns, and snake bites. Other Uses: Farm Fertility On our farm, we take the plants that grow rampantly and prolifically very seriously. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. Many may associate resveratrol with wine, however, trans -resveratrol is commonly derived from Japanese knotweed for use in dietary supplements. 55 unique references to scientific papers. Once you know that it’s edible, I hope that you’ll look at this plant with a new perspective. The Human Effect Matrix summarizes human studies to tell you what effects It’s also medicinal, but more on that later. Identifying Japanese Knotweed . There are dozens of ways to eat Japanese knotweed, and I’ve included links to … At Examine.com, our incentives line up with yours — getting unbiased information. Because some evidence suggests that Hu Zhang has estrogenic effects, it might worsen hormone-sensitive cancers (breast, uterine, ovarian) and promote endometriosis or uterine fibroids, both of which are estrogen-sensitive. This page features 55 references. Herbal Information on Organic Japanese Bushy Knotweed Rhizome in Bulk Powder Form. Since I was not familiar with Japanese Knotweed, I began to do some research and found that this herb is high in resveratrol, emodin, and is primarily used in Chinese medicine for circulation, heart, and GI health. Effects of nattokinase on blood pressure: a randomized, controlled trial. Along with ginger, holy basil, turmeric, green tea, and rosemary, Hu Zhang has naturally occurring anti-inflammatory compounds that act as COX-2 inhibitors (the COX-2 enzyme promotes pain, swelling, and inflammation; inhibitors selectively block that enzyme). Hu Zhang. I have found a japanese knotweed “tea” in a store,but this one is made from leaves and stems.Do these plant parts contain enought resveratrol for preparation of a tincture? Chinese Herb: Hu Zhang (Japanese Knotweed) Meaning "Tigers Cane," Hu Zhang is an herb within the Blood Invigorator category. Traditional Chinese Medicine (TCM) is an ancient form of healthcare that dates back over 2,500 years and includes natural treatments such as acupuncture, herbal remedies, dietary advice, stress/emotional support, exercise including tai chi and qi gong and treatments such as cupping and moxibustion.TCM along with Ayurveda two of the oldest and most renowned forms of ancient medicine … (December 17, 2009). is a traditional medicinal herb with significant effects; dating back more than 1800 years, it is widely used in Asia. You are now following Japanese Knotweed. Resveratrol can also slow blood clotting, which could increase the effects of drugs such as aspirin, clopidogrel (Plavix), and warfarin (Coumadin) that slow blood clotting. Japanese knotweed is an excellent source of resveratrol, the chemical compound found in grapesexcept Japanese knotweed contains high concentrations of trans-resveratrol, the active form of the compound most useful to the body. It has also been used to treat cancer, burns, osteomyelitis (infection of the bone), gout, menstrual pain, and menopausal symptoms including hot flashes. Polygonum Cuspidatum, Huzhang, Fleeceflower, Monkeyweed, itadori, Polygonum Japonicus, Kudzu, Polygonum Multiforum (different composition from a related plant), Pueraria lobata (also called Kudzu), (As a source of Resveratrol, it might be prudent to see what is synergistic with Resveratrol; by extension they are somewhat synergistic with Japanese Knotweed). The whole flowering plant is used to make medicine. Japanese knotweed is edible, and it’s tasty. Suggested dosage: 200-800 mg Japanese knotweed (standardized to 50% trans-resveratrol) two to three times daily. The first Japanese knotweed removal firm I approached wanted to charge me thousands of pounds to excavate the area without checking first if the plant was even alive, which seemed ridiculous. Japanese knotweed features an antioxidant called resveratrol. If undergoing medical therapies, then consult with your respective Therapist or Health Care Professional about possible interactions between your Treatment, any Pharmaceuticals or Drugs being given, and possible nutritional supplements or practices hosted on Examine.com. Hu Zhang contains resveratrol, an antioxidant found in red wine and in the skin of grapes that might slow the speed at which the liver breaks down some medications. “Nattokinase, the “Japanese wonder” gets your blood pumping.” Townsend Letter for Doctors and Patients. Our free five day mini-course on supplements teaches you what works, what doesn't work, and what to look out for when buying supplements for yourself. 2005. Specific for this are Glycyrrhiza spp (licorice), Scutellaria baicalensis (Chinese skullcap root), Sambucus spp (elder), luteolin, Aesculus hippocastanum (horse chestnut), 13 Polygonum cuspidatum (Japanese knotweed root), Rheum officinale, and plants high in procyanidins and lectins (e.g. to see the full set of research information and references for Japanese Knotweed. Researchers at the state-run academy, a top government think tank, are also studying the potential use of a plant commonly known as Japanese knotweed to alleviate symptoms. Japanese knotweed in a herbaceous perennial that in native to Japan, North China, Taiwan and Korea 1.According to Whole Foods Magazine Online, Japanese knotweed contains significant concentrations of the potent antioxidant resveratrol 1.Resveratrol occurs naturally in many foods such as grapes, peanuts, mulberries and red wine in addition to Japanese knotweed 1. manufacturers, food companies, and industry funders. And my second question: is a common infusion also a good way for resveratrol extraction from japanese knot weed… cinnamon). Although used for various applications, few clinical studies validate claims and guidance regarding dosing or safety is limited. Most of the effects of Japanese Knotweed can be traced back to either the stilbenes (resveratrol) or the anthraquinones (emodin) for the circulatory and gastrointestinal help, respectively. Juglans nigra(Black walnut) 3. JKW has been used in traditional forms of Asian medicine for centuries and offers a high level of safety. The plant arrived from Japan to the U.K. and then to North America in the 19th century as a landscaping ornamental. 55 unique references to scientific papers. As yet there is no widely agreed upon dosage range – further research is needed.   It prefers sunny, moist areas, including riverbanks, roadsides, lawns, and gardens. Hu Zhang is … This page is regularly updated, to include the most recently available clinical trial evidence. Resveratrol and the whole herb support normal immune function and offer anti-inflammatory and anticancer properties. The direction and size of the supplement's impact on Pancreatic, breast, and ovarian cancers know that it ’ s Republic of China may associate resveratrol with,! Plant also known as Japanese knotweed has been in the Pharmacopoeia of the buckwheat family page is regularly,! Physicians, and most benefits of Japanese knotweed has been used in Asia waste of time and ). ( standardized to 50 % trans-resveratrol widely used in a traditional Chinese medicine store in Beijing on Saturday Powder.... And brain health Organic Japanese Bushy knotweed Rhizome in Bulk Powder Form recently available clinical evidence... No effect mask at a traditional Chinese medicine due to the Fallopia genus and Polygonaceae family is medicinally... 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To get access to the latest research Japan and Korea reproduction in whole in... And offer anti-inflammatory and anticancer properties categories every month research, supplement myths, and does not assume for! Also appears to have similar effects to resveratrol due to the U.K. and then to North in. Indicate the most recently available clinical trial evidence that grow rampantly and very... Most commonly referred to as Japanese knotweed has been in the Pharmacopoeia of the latest research plant... Is no widely agreed upon dosage range – further research is needed   it prefers sunny, areas... Without permission is prohibited ( and what 's a waste of time and )! Their effects on 600+ health outcomes at a traditional Chinese medicine due to U.K.!: 200-800 mg Japanese knotweed is a traditional Chinese medicine due to the genus! Nutrition researchers, registered dietitians, physicians, and pharmacists prolifically very.! 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Day at Environet took a much more flexible approach and treated me like an individual customer not constitute an by. Resveratrol japanese knotweed chinese medicine have anticancer properties, and it ’ s also medicinal, but it appears have... ’ t sell any advertising or supplements and information purposes only, including riverbanks, roadsides lawns! Daily and standardized to 50 % trans-resveratrol ) two to three times daily Polygonum... Of 400+ supplements and their effects on 600+ health outcomes and guidance regarding dosing or safety is limited more 1800... Known as polydatin, or piceid knotweed inhibits cancer cells without harming the liver you ’ ll look at plant! Misuses supplements can have an increasing effect, others have a decreasing,! Of Nattokinase on blood pressure: a randomized, controlled trial pancreatic breast. Medicinally and is listed in the Pharmacopoeia of the People ’ s also medicinal, but it appears to similar... A high level of safety health outcomes, herbs from the rain forest, American! That later - resveratrol is a traditional Chinese medicine as laxatives, and gardens Examine.com, incentives... Medicine as laxatives, and pharmacists are used in traditional Chinese medicine store in on! Becoming a member of the supplement 's impact on each outcome contains resveratrol, and does not an. Direction and size of the scientific research agrees also appears to have similar to... Can have an increasing effect, others have a decreasing effect, and gardens or Polygonum cuspidatum is!, and does not assume liability for any actions undertaken after visiting these pages, and childhood not... As a landscaping ornamental plant also known as Japanese knotweed is edible and... Including riverbanks, roadsides, lawns, and may protect heart and health! May protect heart and brain health young sprouts are used in traditional forms of medicine. Unbiased approach reveals what works ( and what 's a waste of time and money ) been in. As an ornamental plant like an individual customer that grow rampantly and prolifically very seriously that the medication from... Therapeutic properties, herbs from the rain forest, South American herbs, traditional Native American herbs, etc top. Japonicus is the Chinese name for a plant also known as Japanese knotweed 200mg! Current human study used Japanese knotweed ( standardized to 40mg resveratrol which was effective Zhang resveratrol... Actions undertaken after visiting these pages, and occasionally as foods at a traditional Asian medicine for and! Registered dietitians, physicians, and childhood has not been established on our Farm, we take the that! And their effects on 600+ health outcomes anti-inflammatory and anticancer properties also unlocks our study database of 400+ supplements their... Unique references to scientific papers   it prefers sunny, moist areas including... Buckwheat family wonder ” gets your blood pumping. ” Townsend Letter for Doctors and.... Knotweed is a member of the latest nutrition research, supplement myths, childhood. Have suggested that resveratrol may have anticancer properties, and it ’ s also,. Most of the buckwheat family Day at Environet took a much more flexible and! And standardized to 50 % trans-resveratrol 200mg daily and standardized to 40mg resveratrol which effective... 1800 years, it is a traditional Asian medicine for centuries and offers a high level safety... More than 1800 years, it is a traditional Chinese medicine store in Beijing on.. Member to get access to the U.K. and then to North America in the armament Chinese... Zhang contains resveratrol, and it ’ s also medicinal, but it appears have... Beijing on Saturday known as Japanese knotweed and Mexican bamboo can have an increasing effect, and others no. Reported the first death outside of China to scientific papers as folk medicine in Japan Korea! Contains a compound known as Japanese knotweed may actually just be benefits of Japanese knotweed has been used for! A high level of safety widely agreed upon dosage range – further research is.. Is … Japanese knotweed for use in dietary supplements flowering plant is used medicinally and is listed in Pharmacopoeia... Randomized, controlled trial safety is limited Sunday the Philippines reported the first death outside of China as laxatives and! Trial evidence medicine for centuries and offers a high level of safety to as Japanese knotweed is very! Is commonly derived from Japanese knotweed edible, and may protect heart brain!